Genetic Transformation of an Obligate Anaerobe, P. gingivalis for FMN-Green Fluorescent Protein Expression in Studying Host-Microbe Interaction

Chul Hee Choi, Jefferson V. De Guzman, Richard J. Lamont, Özlem Yilmaz

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Great news! Our contributor and his colleagues have recently published their study on the genetic transformation of an anaerobe, Porphyromonas gingivalis.

This bacteria is a common member of the oral mucosa and can cause severe periodontitis and even a risk factor of coronary heart disease and pulmonary infections.

Generally, green fluorescent proteins (GFP) have been used to study bacteria and other pathogens.  However, most of the GFPs require oxygen to be efficient.

This novel research tool that they created utilize an oxygen-independent GFP and is truly a great development in the scientific research field.

See the entire publication here: Research Article

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